What mRNA frameshifting means for therapeutic efficacy
Modified mRNAs have become an important platform for developing vaccines and other new therapeutic approaches. One of the most widely used modifications, N¹-methylpseudouridine (m¹Ψ), can improve protein expression while reducing unwanted immune activation, helping mRNA therapeutics produce useful levels of protein in cells. Can N¹-Methylpseudouridine (m¹Ψ) Affect How mRNA Is Translated? However, recent research has…
AI and the design of mRNA Therapeutics
AI is a useful approach for designing high performing sequences, but its usefulness is enhanced when it is combined with information from mechanistic models.
Welcome to the Jantomarna Blog: Exploring the Future of RNA Therapeutics
We announce the Jantomarna Blog, a forum for discussing the latest developments in mRNA Therapeutics.